Background: Crouzon syndrome ([OMIM] #123500) caused by FGFR2 mutation is an autosomal dominant syndrome with craniosynostosis. the underlying mechanism of which remains obscure. Methods: First. whole exome sequencing was used to screen the possible pathogenic variant in two sporadic patients with Crouzon syndrome. https://lockdownsecuritycanada.shop/product-category/terminal-release-set/